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Are you or a family member experiencing signs of memory loss? We understand that you are frustrated with the lack of answers, individualized treatment and guidance in the traditional healthcare system for cognitive impairment. We understand the pain for individuals experiencing cognitive decline, the frustration of the caretaker and the anxiety of the family members. We’re not here to help you cope, we’re here to reverse the processes that lead to the decline and/or the disease in the first place…

Cognitive Impairment Including Alzheimer’s Disease is a Reaction… Not a Cause

If you can identify and treat the root causes of cognitive decline, you can reverse the symptoms and improve brain function.

“I had over a 75% reduction in Cognitive Decline and TBI symptoms in less than 3-months. Carolina HealthSpan’s program was the best thing I’ve done for my Brain health in the past 10 years! A year after treatment and I still feel as good… maybe even better!”

Joe Delamielleure, Former NFL Player, NFL Hall of Fame Inductee

Traditional System, Traditional Results

Our traditional, insurance-based healthcare system is built for acute care and has developed a mentality of “Diagnose & Prescribe” to deal with chronic disease. Treating complex, chronic disorders with single medications may provide hope to temporarily mask the symptoms, but will not halt the progress or treat the underlying issues. Various levels of Cognitive Decline, including Alzheimer’s Disease, is the culmination of multiple complex, chronic disorders, imbalances and deficiencies, yet our traditional system continues to treat the disease the same way it has for 20+ years…

The Alzheimer’s Epidemic

Dementia by the numbers is terrifying and quickly becoming grimmer. If you have signs of dementia, you should call Carolina HealthSpan Institute to schedule an appointment right away. 1 in 9 Americans currently living will develop Alzheimer’s disease. 75 million Americans have an increased genetic risk factor for Alzheimer’s disease. It is expected that by 2050, over 160 million will develop Alzheimer’s disease globally. But these numbers pale in comparison to the experience of watching a loved one experience a memory lapse, ability to make decisions or function independently. And the numbers are not remotely as terrifying as worrying that your mind may be next…

Don’t Become a Number

The definition of insanity is doing the same thing over and over again expecting a different result. To achieve a different, desired result, you must start with a different experience.

A Wellness Program Worth Remembering

By shifting the traditional disease-centered focus and diagnose & prescribe mentality of traditional medical practice to a more patient-centered approach, our team identifies the underlying, root-causes to disease and addresses the whole person to stop the progression of the decline, reduce symptoms and improve cognitive function.

Different Results Require a Different Experience

  • The ReConnect Program is based off the framework and fundamentals of The Bredesen Protocol® with variations based upon our clinical experience of improving the brain function of over 10,000 individuals.
  • We offer all-inclusive programs designed around your health timeline, objective data, symptom severity, progression of decline, current health needs and future goals.
  • Each program is designed specifically for you and includes education, provider visits, health coaching, advanced diagnostics, various scientifically validated cognitive decline treatment modalities and concierge level support.
  • All programs are based around a time-frame to reach your health goals and include milestones to ensure you are on the right track. Everything is measured at least twice so you will not only feel better, you’ll know why.
  • After your program is finished you may be in a great place to manage your ongoing health on your own. If you desire further care or health-tracking we offer various tiers of membership for maintenance and/or continued optimization.

Dale Bredesen, MD – The End of Alzheimer’s

  • Dale Bredesen, MD is a physician, neuroscience researcher and is internationally recognized as an expert in the mechanisms of neurodegenerative diseases such as Alzheimer’s Disease. He has spent over 25 years studying Alzheimer’s Disease and potential treatments including pharmacological therapies & multi-modal approaches.
  • In 2014, Dr. Bredesen published a landmark study showing reversal of cognitive decline in Alzheimer’s Disease by applying a functional medicine framework to the complex, chronic disease of 10 patients.
  • In 2017, Dr. Bredesen published the now New York Times best selling book – The End of Alzheimer’s, and gave hope and direction to tens of thousands of individuals and families battling the disease or looking for methods of prevention.
  • In collaboration with the Institute for Functional Medicine Dr. Bredesen now trains practitioners in the Bredesen Protocol®
  • Dr. Brown, founder of Carolina HealthSpan, has trained directly with Dr. Bredesen, is certified in the Bredesen Protocol® and our practice is one of the premier referral sites for individuals all over the country interested in this method of treatment.

The ReConnect & ReCODE Programs

  • The ReCODE® program is Dr. Bredesen’s guidelines for reversal of cognitive decline, which can be administered by a physician trained and certified in the Bredesen Protocol®.
  • The ReConnect program is our evolution of Dr. Bredesen’s diagnostic & treatment protocols, including additional technologies, therapies and interventions.
  • Recognizing that systems and processes were the missing piece, holding back many Bredesen Protocol® trained physicians from offering the ReCODE program, we have developed and designed robust systems and models to keep the administrative and medical complexities in order, the data moving in the right direction and the patient at the center of care.
  • We are sharing data directly with Dr. Bredesen and his team in order to collaborate on more efficient and effective models to reach more individuals in need in a more sustainable way.

What Makes Us Different

Individualized, Programmatic Approach

The ReConnect Program is based in Functional Medicine principles. It is an individualized, patient-centered, science-based approach that empowers patients and practitioners to work together to address the underlying causes of disease, reduce symptoms and promote sustainable, optimal wellness.

Applying Today’s Research

The gap between emerging research in technology, effective treatment modalities and lifestyle intervention and integration into traditional, insurance supported medical practice is enormous. This is particularly the case in the area of complex, chronic disease such as Alzheimer’s Disease.

Education & Training Gap

In medical school, most physicians receive less than 5 hours of education on nutrition, sleep, stress or other lifestyle factors. However, these are the main factors leading to chronic disease. Most physicians in traditional practice do not have the time, nor are they adequately trained to address the underlying causes of complex, chronic disease such as Alzheimer’s.

I’m Ready to Get Started

A letter from our founder

Are you experiencing dementia symptoms? Memory loss, confusion, agitation, slowed function, poor decision making, forgetfulness, and maybe even denial? Have you had an exam from a Neurologist and been given a diagnosis of Subjective Cognitive Impairment, Mild Cognitive Impairment diagnosis or Alzheimer’s Disease? Are you scared of what the future may hold for you and your family, or have you lost hope?

As you read further you’ll discover that your cognitive decline can be stopped, and even reversed. With the right program involving a comprehensive assessment, multiple treatment modalities and the right team of medical providers and coaches, you can regain your memory, executive function, focus and quality of life!

Ronald L. Brown, MD

What is Cognitive Impairment?

Senior Moments

We call these living in the wonder years… “I wonder where my keys are?” – “I wonder what his name is?” – “I wonder if I left the stove on?”. Some memory loss is natural, and the tip of the tongue moments or random occurrences of lost words does not mean you have dementia. We do understand that cognitive impairment starts years, and even decades prior to the first symptoms, so if you are experiencing other symptoms in conjunction with a change in your memory, you should get an assessment.

Subjective Cognitive Impairment (SCI)

You can recognize a change, but standard Neuropsychological testing cannot objectively show a decline. In many cases testing may show values “within range”, but these values are not optimal for the individual. This may represent a decline from the person’s earlier ability, but without the true “normal” baseline, there is no way to objectively show decline. SCI often lasts a decade or so before progressing to Mild Cognitive Impairment.

Mild Cognitive Impairment (MCI)

This typically follows SCI. Objective, Neuropsychological testing show that memory, reasoning, executive function, future planning, calculating or other cognitive abilities are abnormal, but the individual is still able to perform the daily activities such as dressing, eating and bathing. MCI may or may not progress to Alzheimer’s, however taking action toward proper assessment and treatment at this stage is critical.


This form of dementia is marked by amyloid plaques and neurofibrillary tangles, however, contrary to conventional belief, there is growing evidence that neither is the cause of Alzheimer’s. Today we have increasingly specific genetic testing and imaging, however Alzheimer’s Disease is usually still diagnosed on the basis of a patient’s symptoms. Once an individual progress to this stage, with the conventional standard of treatment, Alzheimer’s is invariably fatal.


Dementia is an umbrella term for a general decline in neurocognitive abilities. Memory loss is often one of the earlier symptoms, along with confusion, reasoning, decision making, organization, comprehension and future planning. Alzheimer’s Disease is the most common type of Dementia.

What are the Subtypes of Alzheimer’s Disease?

Dale Bredesen, MD, the founding president of the Buck Institute, a UCLA professor and one of the world’s leading Alzheimer’s Disease researchers has developed a new model for Alzheimer’s disease. After 25 years of research, it has been shown that there is no one cause of Cognitive Decline, but rather a multitude of factors creating a snowball effect to steer the brain into decline.

Dr. Bredesen’s lab has identified over 36 factors which fit into three major categories or sub-types of Cognitive Decline. The good news is that all factors are identifiable, addressable and able to be optimized. However, the sooner, the better.

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Alzheimer’s Disease is what happens when the brain tries to protect itself from three metabolic and toxic threats:

  • Inflammation (from infection, diet, injury or other causes)
  • Decline and shortage of supportive nutrients, hormones and other brain-supporting molecules
  • Toxic substances such as metals or biotoxins (poisons produced by microbes such as molds)

To be successful in reversal of Cognitive Decline, you must first eliminate these three threats, remove the amyloid itself, then rebuild the synapses and pathways the disease destroyed.

The Traditional Assessment Vs. Carolina HealthSpan Assessment

The Traditional Assessment
Here’s the average assessment for Alzheimer’s Disease from one of the country’s top Alzheimer’s research and treatment centers:

Visit with a Neurologist


  • MRI of the Brain (without Volumetrics)
  • MoCA – Montreal Cognitive Assessment


  • Complete Blood Count
  • Metabolic Panel
  • Thyroids (no other hormones)
  • B12


Keep an eye on disabilities, including decline in ability to manage money, medications and transportation.

Treatment Options:

Donepezil – Aricept

Carolina HealthSpan Assessment

What Does our Assessment Look Like?

  • MRI of the Brain with Volumetrics for Hippocampal Atrophy
  • qEEG of the Brain for physiological function and communication between networks
  • Computerized Brain Function Testing (Memory, Executive Function, Attention, Flexibility, Processing Speed)
  • Montreal Cognitive Assessment (MoCA)
  • Neuropsychological Assessment
  • Physiological response to stressors
  • Heart Rate Variability
  • VO2 Max
  • Sleep assessment
  • Lifestyle assessment (Nutrition, exercise, stress, sleep)
  • Body Composition


  • Genetics including APoE-4 status
  • Inflammatory markers
  • Hormonal function (full hormone panel)
  • Insulin resistance
  • Metabolic Pannel
  • Toxin exposure (metals & biotoxins)
  • Microbiome status
  • Gut and Brain Permeability
  • Nutritional deficiencies & food sensitivities
  • Fatty & organic acids


Identification of your Cognitive Decline subtype and a detailed step by step, individualized program to address all deficiencies, attack the multiple root causes of decline, modify lifestyle design, halt and reverse cognitive decline.

The Essential Tenets of Cognitive Decline Treatment

For reversing cognitive decline of any type, at any stage in the decline, the following must be addressed and optimized:


Whether you have leaky-gut, food sensitivities, nutritional deficiencies or simply a poor diet, you need to know exactly where you stand and have a nutritional plan in place to support your brain and body.


Various forms of exercise support brain function. Other’s do not. There is proper exercise for your body as you age, and proper exercise for your Brain. An optimal program can be designed for you depending on your current state and needs.

Stress Reduction

Stress is known as the #1 proxy killer, and although you may not feel “Stressed Out” it’s much more about how you handle stress when it does appear.


The overwhelming majority of hormone receptors are in your brain. Hormones are a major control mechanism for how we feel, act and whether we decline or are protected from future disease.

Toxin Elimination & Avoidance

There are toxins all around us. In our food, our water, on the grass we walk on, the air we breathe and in our body (and potentially your brain). The first step is to assess what you may have in your system, then remove it.

Cognitive Stimulation

How often do you challenge your brain? Do you challenge it in every way it needs to be challenged to remain strong across the board? Various Cognitive Stimulation techniques have been proven to decrease the risk of Dementia by up to 30%!

Specific Supplementation

Brain supporting nutrients are important regardless of the stage of decline or sub-type. There are specific supplements that people need because of deficiency and other than everyone past a certain age should take for protection.


Proper quality and quantity of sleep is imperative to brain restoration. It is only during quality sleep that our brain recovers and repairs through a process known as autophagy.

Neurofeedback & Neuromodulation

Neurofeedback and Neuromodulation are safe, effective, painless and side-effect free ways to reset, reorganize, rewire and upgrade the computer in your head.

Light Therapy

Infrared light and cold laster therapy have been proven effective to help recharge your mitochondria, and have been shown effective in reducing the symptoms of Cognitive Decline.

Health Coaching

Having a blueprint for success and a coach to guide you there is significantly more efficient than trying to get there on your own. First step is to clearly define your goals, then find someone with experience and expertise in helping people achieve those goals.

Why a Comprehensive Program is the Only Model Shown to be Successful in Reversing Cognitive Decline

To date, 244 potential Alzheimer’s drugs have gone through extensive clinical trials. 243 drugs have failed these trials, showing no improvement vs. placebo and in many cases worse decline.

Only one drug in over a decade has passed the FDA’s guidelines, it has a minimal effect in the best cases
and comes with its’ share of side-effects.The idea of a Mono-Therapy for Cognitive Decline needs to be put to rest.

It takes years and in many cases decades for symptoms of Cognitive Decline to appear. This means your lifestyle, environment, diet, injuries, exposures, infections and more have lead to this point. The only way to halt and reverse the decline is to fix what caused it in the first place.

Your Children Don’t Want to Take Care of You!

The average expense of individual dependant care is $5,000-$10,000 per month. Unless you have long-term care insurance, this is not covered under any health care policy including MEDICARE. If you or a loved one is experiencing Cognitive Decline, where will you/they be in a year if you stay on the same path? How about 3-5 years?

It’s time to join the thousands of individuals who have seen their Cognitive Decline reversed through the Bredesen Protocol® and our ReConnect Program.

What is the Next Step?

Step 1

Start your experience with a 20-minute call with one of our cognitive decline experts to determine if we’re a good fit for your case.

Step 2

Then join us for free, in-house education on the topics of Functional Medicine, Brain Enhancement & the Reversal of Cognitive Decline.

Step 3

Collect some specific objective and subjective data including advanced Labs, Brain Function Testing, Lifestyle Assessment, Symptom Profile and Health Timeline.

Step 4

Finally, sit down for a 1-on-1 results and program design conversation with one of our Functional Health Experts to determine if you’re a good fit for our practice.

If Steps 1-4 are followed, your road toward your health goals can start immediately!


Reversal Of Cognitive Decline: A Novel Therapeutic Program

Dale Bredesen, MD – Founding President, Buck Institue

Summary A novel, comprehensive, and personalized therapeutic system is described that is based on the underlying pathogenesis of Alzheimer’s disease. The basic tenets for the development of this system are also described. Of the first 10 patients who utilized this program, including patients with memory loss associated with Alzheimer’s disease (AD), amnestic mild cognitive impairment (aMCI), or subjective cognitive impairment (SCI), nine showed subjective or objective improvement. One potentially important outcome is that all six of the patients whose cognitive decline had a major impact on job performance were able to return to work or continue working without difficulty. These anecdotal results suggest the need for a controlled clinical trial of the therapeutic program.

Dale Bredesen, MD has published two peer-reviewed articles since 2014 which have confirmed the data in his 2014 study.

Summary In summary, these results for our Brain Fitness Program for patients with MCI further support the fact that a multi-disciplinary set of interventions has the potential to enhance cognitive function in elderly (4). It provides an additional incentive to initiate large placebo-controlled randomized clinical trials to evaluate the possibility that we can slow the rate of cognitive decline with aging, and grow the size of hippocampus, through an emphasis on diet, exercise, cognitive stimulation, neurofeedback, meditation, and counseling for stress reduction and having a purpose in life.

Our goal is to safely and effectively optimize your health in the most efficient manner using trusted and advanced solutions.

Your outstanding experience at Carolina Healthspan Institute is at the center of our healthcare model. Experience the benefits that 30 minutes or more with a physician can mean for your health.

Let's Get Started!


What you have is not why you have it! Download our Free Report on Reversing Cognitive Decline. Start your experience with a 20-minute phone call with one of our functional health experts to determine if we are a good fit for your case.

The time is now to take control of your health. And it's all possible with the right guide.

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