Troches are small lozenges that dissolve between the cheek and gum over a period of about 30 minutes. As it dissolves, the hormones are gradually absorbed into the blood stream, resulting in physiologically natural hormone blood levels. Also, because these are bio-identical to the hormones your body has produced, they are efficiently recognized, utilized, metabolized and excreted by the body. Since your own hormones only last about 8 to 12 hours, your natural hormone replacement should be dosed about every 12 hours to give adequate, even blood levels.
Artificial hormones, however, do not fit receptors exactly and are more difficult for your body to metabolize. That is why they are usually dosed just once per day.
Because of the tremendous advantages in consistency, effectiveness and the ability to avoid the digestive process, many doctors and patients prefer troches as the primary dosage form for hormone replacement therapy for both men and women.